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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0b83dacd493ddc541520f93ecd537e98f278bacd8e4e31a81305d0116aa0c85' 
  AND token = 'OMXY+BlXHaIETxaDnhjzuCEDqndl85vM/pJd8KyNkWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}