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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb2c9f8a095a08c26e083c1eb0289c3e51dcf6a6ffb2d43c67821de76c00cc85' 
  AND token = '2/0NIkGWrhGje+C/dMx6FUslEDGUQuqykNAj4hnbUeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}