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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2395d9a0c299514f59166921eae14ac733f2c167b7b2f691c8abc44b0824f6ab' 
  AND token = 'jy5oe/Kk0jiccF/bFh20zIaMpbt+oIN/H1yQn8mUjaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}