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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16376d15e7942a3732239dfab598848f8d7ca2833021d03936cda53f5d17b5b6' 
  AND token = '8jCQ7P+aFneT/7n+ammKsKZhAm+9VN5FscBkQiyxCWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}