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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8eeccb3ae2734a83f6a8c6de4b2013a2960a0a003ef3ba1bb25fe97d5952b80' 
  AND token = 'mMe+rJ0nzeDIQlUpqxNid3nFLv/cx/kGiC32SmvG4hM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}