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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0bd99adf5774e261e981d296ee8aeb197461e0d54c335883ac0e08493b70b7c' 
  AND token = 'pAfVIsfxVqHznPG/2gELUo344AYtZYT2Up8AxLkZHos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}