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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95ec025810555bdf8a70b7e892e93ddc4cbe9baf08c19218281aab8f7504f4ef' 
  AND token = 'TvMWSNgJ3KN5AvTGu2fDydvGw+Z0IXuMiXG5UxnLddg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}