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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4bd17c5642bda498f1b53241dd6d375cb521db4e4a8171ca142502bd8656c5' 
  AND token = 'NXsLoRSwjAq22GRXH0fNjv+hRE5O1tChvVaC4DdoFfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}