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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b021db6f9751d5a85adfb43b80c65bdc3a2946f0ccff8fcc65d7dbc802143dd' 
  AND token = 'JmC3mNaw37G3E9INCEQl/t10Hk+9t36JYqvbC94s56o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}