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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4dd6b50bbcc61294ffed6cc84c986a6cbfe2eb0e2a7e7786f1bc364b9c65ffb' 
  AND token = '9s+DX+r1Oko1Kpmp8un6ou95GzyrS/zQHmtRIdOpQHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}