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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'becd3bd355ed737d8bb3fe793c88101e30608e7d73632630e05315e3c00fbd2e' 
  AND token = 'MJiCSw6g+DcAf1B85ONWHDfW+UdBrRUgZpCFTRb58nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}