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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c203678535414cf272fe934b31f78f1acdd1cc46298a2f4cadea43d41a382b14' 
  AND token = 'n6ZQ7pu+Ia39+sMoj0C7ZE4B5YnwppHGb2cosdjK3bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}