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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00512a8eccb7e3d707c4263c786b05b9fafced2e9057d029226ccdb0b0cb6d46' 
  AND token = 'W6EbjSGKFCiduGyUuNqgt+NJL1BVg06RxJTgmsU1v4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}