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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9839baffe0d942e2b9ea0aca0425b6c0541cacf0d0bb8c31f0d806f97bcf9d78' 
  AND token = 'ZA8MwQRSgwwZ+uugBW1vX2zNSRN602GcvO/PL/lUs1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}