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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420a5e25ddf861fa52f5c31df55d2419c05e66bb9aeab0ce5fe8a58664b61a68' 
  AND token = 'wmRMBoBt0rE1wR0Hnvc9BWOdMz4DRB5zyAhHMVZUF60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}