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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6e75fb6c362eb1fe11589ab4d84739a62b73ba259a9267823c61282d4d7f7c' 
  AND token = 'h5Q7TVFa47n0TYMeC4M1W6HncycTxvQgO8Z+3K3PlGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}