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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ab0acfdf75d1059cb2c1082e477e90386066e4c2ba396deb703545ab48b5641' 
  AND token = 'IMaZSRZgDxl0k2AwDon+7G9MaZHTu8Y88NYaVWC91SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}