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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff9a02301c7be4b9366bb483c0b5511f27c56aaceb1a0ef216d3e23f31a08085' 
  AND token = 'nVQKN53KLnb+jbDe1PwdqLBJ/wU5NxPc27q6ayFpTaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}