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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f75a2233d6714d95503fec901716cf58d3d28e3d1dffa20e66c3db000617be4' 
  AND token = '25LAtDVwOTmjjQrgwhKZ+WEyJm6JQSwcN+jfk1+LgXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}