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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f980d2f7ddaf494b692ef5ddee99506a1df45608784f725312af86915e6566' 
  AND token = 'g4U6zSIbcKWpjfmnd0euqeX8tgxlH0ICpl5c6OoI+Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}