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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a61f2492323915022f01c3e85ad53d0a21d234a1d21d4538f3f227b6b014c82' 
  AND token = 'DnHPxYFsc6PKtPkk1+LiIVr0VvyTkSz24G305glre6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}