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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6def69e78d3ca726ab97c7be16fd94457ee213f13d8607c8f405187dd4c56c07' 
  AND token = 'mQ7uElPsxm7WAp/tMlfe4D4R90V/x+rbJkDMfZdRBlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}