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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea59246e947a56de2d82ba5f1ffdb5b8e0be9bfa1bf5b3d973eb5b1229e4dd6b' 
  AND token = 'm3fE9Bz7IAVrRPqxv6cRK6niJSVngz3sbZ+3gBf3QFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}