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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5386bbb9ecbb13b643457c83c59dcc269e6c44e674c7dce67acf81fc6f6ba749' 
  AND token = '+nbkqj8Bn6CND/BiDEKHCWKA1GvFCcVGfRk1filze2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}