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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c853982cf03d8d236f3f3df60209e93b792e3cff511f915cbf7b1af8f7b0329e' 
  AND token = 'bmiUCdWOnFiJFMeCKpC0IxZl9OqLjrlgsLVvZEvFYLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}