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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da0b6c40aedd67d70bf910e9fa385220a2ff6c9c61d354c6f69cd0f39bcbe79' 
  AND token = 'tJ713o8TVYCvyO/7FWPS1x+VgvQya/LSSS4j1Ie6GF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}