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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757b89ed38ef52c1ac42d04cb1bb5eb4966340f6f2711d28620c9d81f486b3dc' 
  AND token = '0e+XJ0WMd3BZOQ8C9H2pQVzx6+FX18NnGDCt7fg0Ke4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}