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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fa96aee6b413dd7d5e55c10ba6d9feb1b58d441aec48fd069f210277c355945' 
  AND token = '12PUMZQKI5rwbra6uZNIqmww5a1p8q1NZqskPmg4bRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}