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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2d901c88cbbc9067667cde0ee0b27236423887bd48d429a8be036d3ef7d492' 
  AND token = 'Og9FAkSpL3kW24d4XYs8RaR28v8IF53KQ7+yKo1hwpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}