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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48499771aaabb433682d3ffeb13b40e1ca24ae025e7a48bd8a0dea2258f0ace0' 
  AND token = 'EcKc10PDdlbTBgjsTc+uGtlJ+Fn5ebIKaNNX/++9kKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}