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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d7f8266d973303a6f7be3cbe8ed766a11b534e1e887fee8a88a95461880907' 
  AND token = 'jfwyihLenY1vW5CxucPI6aiL6auNLFm9CDQ6IOf6fYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}