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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19cf9cb19c3eacd8928f225c44f949a9d95a0499b2522ca918adbeef4e9b1b6d' 
  AND token = 'vL7vLbXPsQ2zHNmSZCBCNvkyWyu7K18KwAcC4d7QBZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}