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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a28775cf3f66846ce1b0fbdd0d51aa86b021f477717c42845c262d99f93da446' 
  AND token = 'u470zlKDo7RuIgglia0lglNmLha6d9USvcW25QMWNdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}