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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4a1adc33280f4ec9326d053b00c8720ddc9681b926400025c5eb77dfe1aaeb' 
  AND token = 'R6L1/wVGrWmeORyBnto0jorSUv0wQg/qC3yW28zpPu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}