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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e33dc4621ce7d7dd0afee649b1d4b0d16ea13a2c56e8f9504560297144308d8' 
  AND token = 'EBjSpcw+0XjxayoTZXHI8gEdTfOtXatInqr7OHI7SJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}