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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7666a8451f7afb0c615f54d5df73533dd076481cdbd2fe71fe8b48a5f4dc5d40' 
  AND token = '+SCdHGjmLDMl+pgpL4OR20335OmBt3B69aRQC9/YXnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}