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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41e3e9a19d0d9c1ff5cafbc8455b3f42d08a4cc02307d35a4e5f1aaec7a8128' 
  AND token = 'ZBBsPlmozxFUm53CuJiU5P+8AKYTMtFHEDgJH4/y7GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}