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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b4e1295a72c750093ecd796915b18c80983ae84c9ecb5a045ff177fd42fb5b2' 
  AND token = 'bU8/kyWBLNpbugD7ddP9Y4okKKdBx5bSv/28Boemzpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}