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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8588f75a770ced55fbf2669e21556c56a429654f362e17f4d266634a9163d603' 
  AND token = 'YCoNGLbNukLdRs23Ecno1SXgoZF8ewHwjoUXgCqSTnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}