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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b00da3e16fcec4db9c07d71cd3bfbb4e581b09f52ed9b00dd93a93dc8b8f129' 
  AND token = 'L4RMvvf1OhJmR/X+nLwc/kLwHhQl3qMM385JT/k45kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}