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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da2c8c0321a337536c3257ef689ae6b00fa40c89dd1e96ae57843ed3b098bc19' 
  AND token = 'et+AUMF8MzCRRgv8xQeOxJa/kqSNjyuZZQ7tyu4HQ1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}