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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4000b24a206da19f629d13557d01948d3ce0473542f94d4f40b111fb05bf9e29' 
  AND token = 'z9XlNneqwZH6EGLS1MnXdPAB/lce7A+nDqGyAddZ0rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}