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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca14ae65e0dce7b44b21ed28a2a157cb850f1bb8c406f49bfb3619d20f4f744d' 
  AND token = 'GGJKXIRfokFXuREhU8k0Sc+x0HOAPYf6Vs0etvA2lx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}