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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a45de46100b109055ba759cb66a2618ea14490896729626926d058fa4aa3d8f' 
  AND token = 'h/oMujkRZSMD4qLnEdRHUC5IJJpcrb2MhcT0GV04vwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}