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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6546aeaa595a24ffa7167bf62ca215a053f04347c9f9370e9eb66e25648a7c29' 
  AND token = 'XH72qYnNFDf58ldD7FiMemZGHbCirkgs2l/C4wbFizk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}