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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf48913424110854892ee684fc16b78884afaf493e94bb55783bb7995e8ff094' 
  AND token = '0SLC+7qwDA7aJVGdJVj0v2P+Lq4/2/ZbcvqwWDM43co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}