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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f8018013c9a0a2834c1158dc63fefb0de5c9df26b8bc5eeaf4f38af734e636d' 
  AND token = '+Dkg69iD/skHPPQVfz1hedixXheKPtdeElAz19W2HmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}