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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2a9a5e23aef26b19509ecb41726a49167881429b3a57c8a68b65389dfccf269' 
  AND token = 'QWl44kTwV2Ox0M7GdGoLlL8+zkDFyNVhiYVz/kY0GyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}