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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79289cb251f6d0b3a9e3e676aaf236cfdace0e5e3f9f3e06ea116a4cd9f69729' 
  AND token = 'NXgPLVohBvVYSCr6WdW++Zt9IKiTSmgA3Qy72kgPJnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}