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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0d12eb69c11212d8fb3d23609f6d4e0c2721dc5f09417eeb82bdbbf0965447' 
  AND token = '5zX+Q4QaBUxko8rEJ/rv6l/DG5mr/RF5BioLXtZy5M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}